About Manly Haematology
Manly Haematology is the innovation of Dr Amanda Hugman – a clinical haematologist who lives locally on the Northern Beaches.
We are a private clinic where general practitioners and other medical specialists refer patients for the diagnosis and/or management of a haematological disorder.
Our focus is on ensuring that your journey from haematological diagnosis to treatment is streamlined and supported. You will be provided with a comprehensive explanation, and expert management in an ongoing relationship.
About Dr Amanda Hugman
Fellowships and Qualifications
Dr Amanda Hugman is local specialist haematologist. She is a physician with fellowship training in both clinical and laboratory haematology. Dr Hugman completed medical training at the University of Sydney.
She undertook physician training at Royal Prince Alfred Hospital Sydney (RPAH) gaining dual fellowships with the RACP (Royal Australasian College of Physicians) and RCPA (Royal College of Pathologists of Australasia). Post-graduate fellowship was undertaken at Cambridge University’s Addenbrookes’ Hospital.
Undergraduate medical electives were undertaken at the University of Cape Town’s Groote Schuur Hospital and the rural township of Gove in the East Arnhem Region of Australia’s Northern Territory. During her post-graduate fellowship at Addenbrookes’ Hospital in Cambridge she worked in the Department of Haematology with world-renowned experts, Dr Trevor Baglin (Thrombosis and Haemostasis) and Professor Tony Green (Myeloproliferative disorders).
Dr Hugman was awarded a Cancer Institute Clinical and Research Fellowship to complete research in molecular haematology at Royal Prince Alfred Hospital in 2007. This was undertaken at the Institute of Haematology RPAH under the supervision of Professor Harry Illand. She completed a Masters of Philosophy in Medicine (University of Sydney) and published a thesis entitled ‘Analysis of Molecular Aberrations in Acute Myeloid Leukemias’ in 2011.
Awards
2007 NSW Cancer Institute Clinical and Research Fellowship in Molecular Haematology.
2008 HSANZ Haematology & Oncology Targeted Therapies Fellowship completing a research project on of MEG3 and DLK1 expression in patients with AML.
Clinical Appointments
Dr Hugman is a Staff Specialist Haematologist in the Department of Haematology at St George Hospital in Kogarah. She divides her working week between St George Hospital and the Manly Haematology private practise. At St George Hospital she provides clinical care in the inpatient and outpatient setting. She manages patients with benign and malignant conditions including the provision of inpatient and outpatient chemotherapy and Autologous Bone Marrow Transplantation. She is a member of the St George Hospital Lymphoma Multidisciplinary Team.
She has a dual appointment with NSW Pathology and as such she provides supervision in the Haematology Laboratory of tests important in the diagnosis of haematological diseases. These include bone marrow biopsies, blood film interpretation, haemostasis, and platelet testing, haemoglobinopathy investigation and transfusion testing.
Dr Hugman provides lectures to St George Clinical School students and takes part in the undergraduate and post graduate Basic Physician training program. She has held responsibilities for safety and quality and clinical research at St George Hospital. Dr Hugman is passionate about clinical research and is an active participant in the St George Haematology Clinical Trials Unit. Dr Hugman is a sub-investigator on several malignant haematology trials. She is currently the Principal Investigator for two trials investigating the management of ITP and the management of Myelofibrosis.
Key Publications
Hokusai post-PE study: a follow-up study on long-term outcomes of pulmonary embolism in patients treated with edoxaban vs warfarin
Ingrid Bistervels, Wim Boersma, Roisin Bavalia, Karina Meijer, Peter Verhamme, Hugo Ten Cate, Jan Beyer-Westendorf, Sebastian Schellong, Barbara Hutten, Michael Kovacs, Marco Cattaneo, Waleed Ghanima, Amanda Hugman, Michiel Coppens, Marije Ten Wolde, Dominique Stephan, Nicolas Falvo, Dominique Brisot, Isabelle Quere, Saskia Middeldorp. European Respiratory Journal 2020 56: 3581 https://erj.ersjournals.com/content/56/suppl_64/3581
Use of arsenic trioxide in remission induction and consolidation therapy for acute promyelocytic leukaemia in the Australasian Leukaemia and Lymphoma Group (ALLG) APML4 study: a non-randomised phase 2 trial.
Iland, H.J., Collins, M., Bradstock, K., Supple, S.G., Catalano, A., Hertzberg, M., Browett, P., Grigg, A., Firkin, F., Campbell, L.J. and Hugman, A., 2015. The Lancet Haematology, 2(9), pp.e357-e366.
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(15)00115-5/fulltext
Triple therapy for Immune Thrombocytopenia: A Novel combination of conventional strategies to safely sustain platelet counts in ITP.
Philip Young-Ill Choi, Soo-Chin Ng, Christine Lee, Fernando Ron Colato, Xavier Badoux, Amanda J. Hugman, Sundra Ramanathan, Shir-Jing Ho, Szu-Hee Lee, Beng Chong Blood 2013; 122 (21): 1084.
https://ashpublications.org/blood/article/122/21/1084/103272/Triple-Therapy-For-Immune-Thrombocytopenia-A-Novel
All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4).
Iland, H.J., Bradstock, K., Supple, S.G., Catalano, A., Collins, M., Hertzberg, M., Browett, P., Grigg, A., Firkin, F., Hugman A. and Reynolds, J., 2012. Blood, The Journal of the American Society of Hematology, 120(8), pp.1570-1580.
https://ashpublications.org/blood/article/120/8/1570/30826/All-trans-retinoic-acid-idarubicin-and-IV-arsenic
Analysis of Molecular Aberrations in Acute Myeloid Leukaemias
Hugman, A., 2011. University of Sydney. (Thesis)
Hepcidin: an important new regulator of iron homeostasis
Hugman, A., 2006. Clinical & Laboratory Haematology, 28(2), pp.75-83.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2257.2006.00768.x
What Do We Treat?
Manly Haematology specialises in benign (non-malignant) blood disorders. Examples of the types of disorders treated at Manly Haematology include:
• Clotting Disorders
– Deep Vein Thrombosis
– Pulmonary Embolism
– Anticoagulation Management
• Abnormal Blood Counts
– Anaemia
– Polycythaemia
– Leukopenia and Leucocytosis
– Thrombocytopaenia and Thrombocytosis
• Bleeding Disorders
– Haemophilia and Von Willebrand’s Disease
– Platelet function abnormalities
• Inherited Blood cell disorders
– Thalassaemia
– Sickle Cell Anaemia
• Paraprotein disorders
– Monoclonal Gammopathy of Unknown Significance (MGUS)
• Investigation of splenomegaly or lymphadenopathy
Treatments such as blood transfusions, iron infusions, or venesections can be arranged through local hospitals if required.
The focus of Manly Haematology is benign blood disorders, however we can also assess and manage patients with certain malignant conditions. These include low-grade leukemia/lymphoma and pre-malignant conditions such as Myelodysplastic syndromes and Monoclonal Gammopathy of Unknown Significance (MGUS). If hospital management is required, we can arrange referral for treatment in a local tertiary hospital.